Minimally Invasive Neuropathy Treatment — Not a Permanent Implant
The NS100 by NeuroDynamics Global is an FDA-cleared 20-day temporary neuromodulation therapy. Treatment is minimally invasive and is performed during an office visit, with patients returning home the same day. The treatment setting must comply with applicable state requirements and the treating clinician's assessment. No permanent hardware, no opioids.
Why patients ask for minimally invasive neuropathy options
For many people with painful diabetic neuropathy, the choice has historically been between long-term medication and a permanent surgical implant such as a spinal cord stimulator (SCS). Both come with significant trade-offs — medications can carry systemic side effects, and permanent implants involve surgery, ongoing maintenance, and the possibility of a removal procedure later.
The NS100 by NeuroDynamics Global was designed for the patients who fall between those two options: people who want more than oral pain medication can offer, but who are not ready — or not appropriate — for a permanent implant.
Key facts
- Treatment is minimally invasive and is performed during an office visit, with patients returning home the same day. The treatment setting must comply with applicable state requirements and the treating clinician's assessment.
- No permanent implant — device is removed after 20 days
- No general anesthesia — placed under topical anesthesia
- No opioids — non-pharmacologic therapy
- FDA-cleared Class II medical device
- Covered by Medicare for eligible patients
Why it matters
In-office procedure
Treatment is minimally invasive and is performed during an office visit, with patients returning home the same day. The treatment setting must comply with applicable state requirements and the treating clinician's assessment.
Temporary 20-day therapy
The device is worn for 20 days, then removed in a simple in-office visit. Nothing is left in the body.
No permanent implant
Unlike spinal cord stimulators, NS100 leaves no permanent hardware behind — no battery to replace, no permanent device to remove.
Targeted nerve therapy
Delivers gentle electrical stimulation directly to peripheral nerves to help modulate pain signals.
How a minimally invasive 20-day therapy works
NS100 is a peripheral nerve stimulation (PNS) system. A thin lead is placed near the peripheral nerves involved in your pain during a brief in-office procedure under topical anesthesia. There is no incision requiring stitches and no general anesthesia. Treatment is minimally invasive and is performed during an office visit, with patients returning home the same day. The treatment setting must comply with applicable state requirements and the treating clinician's assessment.
You wear the device for 20 days, during which it delivers programmable, gentle electrical stimulation to help modulate pain signals. At the end of the 20-day window the leads are removed by your provider in a simple in-office visit — nothing is left in the body.
Many patients have reported meaningful pain relief that continues for months after device removal. Individual results vary; your provider will set expectations based on your situation.
How NS100 differs from a permanent implant
Permanent spinal cord stimulators (SCS) require surgical implantation of leads near the spinal cord plus an implanted pulse generator, ongoing programming, battery replacement or recharging, and a separate surgical procedure if the device ever needs to be removed.
NS100 targets peripheral nerves rather than the spinal cord, is placed and removed in-office, and is removed after 20 days. There is no permanent device, no implanted battery, and no permanent device to remove.
Frequently asked questions
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